GSTM1 genetic polymorphism and bladder cancer susceptibility
- VernacularTitle:CSTM1基因多态性和膀胱癌遗传易感性的关系
- Author:
Gangyue HAO
;
Chunxiao XU
;
Mingshan YANG
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Genes;
Genetic,behavioral
- From:
Chinese Journal of Urology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between GSTM1 genetic polymorphism and bladder cancer susceptibility. Methods In a case control study, the GSTM1 genotype was assessed by a PCR based method. 69 patients with transitional cell carcinoma of the bladder and 88 controls matched for age and sex were studied. Results The frequency of GSTM1 null genotype among the bladder cancer patients was 58% compared with 41% among controls(OR=2.0, 95%CI=1.05～ 3.79 ,? 2=4.51, P
