Relationship between Emotion, Severity of Illness and the Effect on IL-8 in Asthmatic Children
- VernacularTitle:儿童情绪与哮喘病情的关系及对IL-8的影响
- Author:
Yi NIU
;
Zhili CHENG
;
Gaohua WANG
- Publication Type:Journal Article
- Keywords:
Asthmatic children;
Emotion;
IL-8
- From:Chinese Journal of Clinical Psychology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To examine the emotional states of asthmatic children with different degrees of severity, as well as the effects of emotion on change of cytokines in airway. Methods: Asthmatic children were divided into two groups according to the degrees of severity: moderate and mild. Their emotional states were measured and results were compared. Correlation analysis was conducted between scores on emotional scales and sputum levels of IL-8.Results: Total scores on anxiety and depression were higher in the moderate group than in the mild group. Negative correlation was found between levels of anxiety and IL-8 during acute exacerbation of asthmatic condition. Conclusion: Emotional distress was found to be increased with severity of asthmatic condition in children. Anxiety contributed to the decreased concentration of IL-8 in asthmatic children's airway.