Mutagenicity of Selenium and Lead and Antagonistic Effects of Selenium on Lead
- VernacularTitle:硒与铅的致突变性及硒的拮抗效应
- Author:
Hua XIANG
;
Jin CAI
;
Mei WANG
- Publication Type:Journal Article
- Keywords:
Mutagenicity;
Selenium;
Lead
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
ve To explore the mutagenicity of selenium and lead, the antagonistic effects of selenium on lead. Methods The ICR mice were orally perfused with sodium selenite (Na2SeO3) at different concentrations of 2.5,5.0 and 10 mg/kg and lead acetate [Pb(Ac)2] at different concentrations of 5,10 and 25 mg/kg jointly and con-tinuously for 3 days, and then the numbers of bone marrow polychromative erythrocytes were counted. Results The frequencies of micronucleus of mice only exposed to 10 mg/kg Na2SeO3, 10, 25 mg/kg Pb(Ac)2 respectively showed higher levels compared with those of control (P
