Study on Chromosomal Damage Induced by Organic Extracts of Air Particulates
- VernacularTitle:大气颗粒有机提取物的染色体损伤作用研究
- Author:
Xuemei ZHANG
;
Zhi ZHANG
;
Xueyi ZHANG
- Publication Type:Journal Article
- Keywords:
Poly aromatic hydrocarbon;
Organic extracts of air particulates;
Chromosomal damage;
Micronu-cleus
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
ve To explore the chromosomal damage induced by organic extracts of air particulates. Methods Some components of polycyclic aromatic hydrocarbons (PAHs) in air particulates collected from highly air-polluted area, Taigang district, and lightly air-polluted area, Yangqu district, in Taiyuan, were analyzed by high pressure liquid chromatography. The chromosomal damage induced by organic extracts of air particulates was detected by traditional micronucleus test in mice. Results The contents of PAHs in organic extracts of air particulates in Taigang area were significantly higher than those in Yangqu area. The contents of benzo (a) pyrene [B(a)p] in air of Taigang area reached 0.819?g/m3, which was more than 10 time as high as that of Yangqu area. The organic extracts of air particulates in two areas both induced the increase of the frequencies of micronucleus of mice, and the dose-response relationships were observed. The mutagenecities of organic extracts of air particulates in Taigang area were significantly higher compared with those of Yangqu area (P
