Effects of Manganese on Frequencies of Micronucleus and Sister Chromatid Exchange in Human Peripheral Blood Lymphocytes in Vitro
- VernacularTitle:锰对人外周血淋巴细胞微核率和姊妹染色单体交换频率的影响
- Author:
Haole ZHOU
;
Lie LI
;
Qian YANG
- Publication Type:Journal Article
- Keywords:
Manganese;
Micronucleus;
Sister chromatid exchange
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
0.01). A sig-nificant dose-reponse relationship was also found between the manganese exposure doses and the frequencies of mi-cronucleus and SCE in experimental group. Conclusion Lower exposure levels of manganese of ≤0.25?g/ ml were safe to genetic materials, but higher manganese exposure levels of ≥0.75?g/ml might cause different kinds of DNA damages.
