Curative effect of Serratia marcescens vaccine in treatment of malignant pleural effusion
- VernacularTitle:粘质沙雷氏菌苗治疗56例恶性胸腔积液
- Author:
Bing LU
- Publication Type:Journal Article
- Keywords:
serratia marcescens vaccine;
malignant pleural effusion;
cisplatin;
fluorouracil;
chemotherapy
- From:China Oncology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the therapeutic effect of serratia marcescens vaccine(S 311 ) in treatment of malignant pleural effusion. Methods:56 patients with malignant pleural effusion were treated with serratia marcescens vaccine, another 32 cases were treated with DDP and 5 FU as control. Results:Response rates were 94.6% and 78.1%. Average effectual times were 9.7and 17.2 days. Statistical difference was noted between these two groups. The toxicities in group SMV were fever and thoracalgia .No other serious side reactions occurred in group S 311 . Conclusions:The therapy with S 311 can effectively control the malignant pleural effusion. The effect was quick. The side effect was light and this treatment can improve the life quality of patients. Therefore, it is warranted for wide use.
