Central executive dysfunction in patients with obstructive sleep apnea syndrome: an event-related potential topographic study
- VernacularTitle:睡眠呼吸暂停综合征患者工作记忆损害的事件相关电位脑电地形图研究
- Author:
Xi ZHANG
;
Shunwei LI
;
Yuping WANG
- Publication Type:Journal Article
- Keywords:
Sleep apnea syndromes;
Anoxemia;
Memory;
Brain mapping;
Evoked potentials
- From:
Chinese Journal of Neurology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the early effect of hypoxemia on central executive function of working memory.Methods 24 patients with obstructive sleep apnea syndrome (OSAS) and 20 healthy matching controls were studied in probe retrieval task.Results In control group,both the low and high conflict identification tasks elicited the N270 component with right prefrontal [F4,(2.2?2.7) ?V]and posterior [P3,(7.0?3.0) ?V; P4,(6.9 ? 3.1) ?V] distribution. N430 was elicited in high conflict condition with right hemispheric lateralization. The positive component,P300( 300～400 ms) distributed remarkably at parietal scalp[P3,(7.0?3.0) ?V; P4,(6.9?3.1) ?V]was elicited only in identity identification task. The N270 was significantly decreased in the frontal regions in mild OSAS patients [F4,(5.0 ? 4.5) ?V]; F3,(6.0?4.5) ?V] in comparison with the controls( P
