Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes.
10.3341/kjo.2010.24.4.213
- Author:
Song Ee CHUNG
1
;
Dong Hui LIM
;
Se Woong KANG
;
Young Hee YOON
;
Ju Byung CHAE
;
In Ho ROH
Author Information
1. Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. swkang@skku.edu
- Publication Type:Original Article ; Comparative Study
- Keywords:
Optical coherence tomography;
Photoreceptor;
Visual acuity
- MeSH:
Cell Survival;
Female;
Follow-Up Studies;
Humans;
Male;
Middle Aged;
Photoreceptor Cells, Vertebrate/*pathology;
Prognosis;
Retinal Perforations/*pathology/physiopathology/surgery;
Retrospective Studies;
Tomography, Optical Coherence;
Visual Acuity/*physiology;
Vitrectomy/methods
- From:Korean Journal of Ophthalmology
2010;24(4):213-218
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs). METHODS: Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Correlation analysis was conducted between postoperative visual acuity (V(postop), logarithm of the minimum angle of resolution [logMAR]) and preoperative factors, including four OCT parameters: the anticipated length (A) devoid of photoreceptors after hole closure, MH height (B), MH size (C), and the grading (D) of the viability of detached photoreceptors. Additionally, the formula for the prediction of visual outcome was deduced. RESULTS: V(postop) was determined to be significantly correlated with the preoperative visual acuity (V(preop)) and OCT parameters A, C, and D (p<0.001). Based on the correlation, the formula for the prediction of V(postop) was derived from the most accurate regression analysis: V(postop)=0.248xV(preop)+1.1x10(-6)xA(2)-0.121xD+0.19. CONCLUSIONS: The length and viability of detached photoreceptors are significant preoperative OCT features for predicting visual prognosis. This suggests that, regardless of the MH size and symptom duration, active surgical intervention should be encouraged, particularly if the MH exhibits good viability in the detached photoreceptor layer.
