Analysis of cyst fluid for differentiating the benign or malignant characteristic of thyroid cyst
- VernacularTitle:囊液分析鉴别甲状腺良、恶性囊肿的临床意义
- Author:
Jia DONG
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Cysts;
Thyroid hormones;
Biological markers;
Lactate dehydrogenase;
Cytology
- From:
Chinese Journal of Current Advances in General Surgery
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To find out an alternative method of determining the benign or malignant character of thyroid cyst.Methods:The color,viscosity,cell,thyroid hormones(T 3?T 4?TSH)concentration,electrolytes and biochemical composition of the cystic fluid were examined in 59 patients with thyroid cyst. Five index were evaluated in determining the benigh or malignate character of thyroid cyst.Results:Almost all malignant lesions had dark red or even bloody cystic fluid.Almost benign lesions had brown or yellowish fluid.Only 4(67%)of the malignant lesions were correctly diagnosed by fine needle aspiration biopsy(FNAB).The mean value of T 3 and T 4 concentration was significantly lower in malignant cystic fluid than that in benign lesions.The mean value of the LDH and isozyme was significantly lower in benign cystic fluid than that in malignant nodules.Conclusion:The combination of multiple variables such as color,thyroid hormone (T 3,T 4), electrolytes,LDH activity(espicially the LDH 1) can provide more valuable data for detecting the feature of thyroid cyst.
