Optic Neuropathy Associated with Castleman Disease.
10.3341/kjo.2010.24.4.256
- Author:
Ungsoo KIM
1
;
Jeong Min HWANG
Author Information
1. Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Castleman disease;
Giant lymph node hyperplasia;
Optic nerve diseases
- MeSH:
Adult;
Diagnosis, Differential;
Disease Progression;
Female;
Fluorescein Angiography;
Fundus Oculi;
Giant Lymph Node Hyperplasia/*complications/diagnosis;
Humans;
Magnetic Resonance Imaging;
Optic Nerve Diseases/diagnosis/*etiology/physiopathology;
Tomography, Optical Coherence;
Visual Acuity;
Visual Field Tests;
Visual Fields
- From:Korean Journal of Ophthalmology
2010;24(4):256-259
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 44-year-old woman with Castleman disease presented with acute visual loss in the left eye. A full ophthalmologic examination and imaging were performed. Visual acuity was 20/20 in the right eye and 20/100 in the left eye. Total dyschromatopsia, a relative afferent pupillary defect, and a cecocentral scotoma were observed in the left eye. Mild disc edema, without leaking during fluorescein angiography, was also observed. Magnetic resonance imaging revealed a small cystic epidermoid-like lesion in the right prepontine and suprasellar cistern. Her visual acuity did not improve and deteriorated to 20/200 in the left eye at 22 months after the initial visual loss. Optic neuropathy may rarely be associated with Castleman disease and suggests a poor prognosis.
