A histological study on experimental implantation of ?-tricalcium phosphate in rabbit mandible
- VernacularTitle:掺铝?-磷酸三钙及掺锶?-磷酸三钙植入兔骨缺损区形态及组织学观察
- Author:
Jianshe ZHANG
;
Shize LEI
;
Chenjun LI
- Publication Type:Journal Article
- Keywords:
Calcium phosphates;
Endosseous dental implantation;
Histology;
Rabbits
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
砄bjective:To study the biocompatability and absorption of ? tricalcium phosphate doped A10 (? TCP A) and ? tricalcium phosphate doped SrO (? TCPs) in the implantation into mandible.Methods:Pieces of ? TCP A,? TCPs or ? TCP (? tricalcium phosphate) in the size of 10 mm?3 mm? 2.5 mm were implanted into the defects of mandible in 48 rabbits.The specimens were obtained 2,4,12 and 24 weeks after operation respectively,measured for size and observed morphologically, the content of Ca,P and S in the specimens was measured with EDAX.Results:The absorption (%) of ? TCP A,? TCPs and ? TCP in 24 weeks was 22,28 and 40 respectively.Bone formation was found in the interface between the mandible and materials in 4 weeks and the amount of new bone in the materials increased in 12～24 weeks.No inflammation was found.The amount of Ca,P and S in the materials was close to that in the mandible of rabbit in 24 weeks.Conclusion:? TCP A and ? TCPs are biocompatable for implantation into bone deffect.
