Study of Cajal interstitial cells in intestine of rats with liver cirrhosis
- VernacularTitle:肝硬化大鼠肠道Cajal间质细胞的研究
- Author:
Jinzhao ZHU
- Publication Type:Journal Article
- Keywords:
liver cirrhosis;
intestines;
Cajal interstitial cells
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the changes of Cajal interstitial cells(CIC) in the intestine of rats with liver cirrhosis,so as to study the mechanism of gastrointestinal dysfunction.Methods: Twenty Wistar rats were equally randomized into control group and cirrhosis model group.Cirrhosis model was established by CCl_(4) in rats.The intestinal motility changes were assayed using Dextran blue-2000 as an indicator.Immunohistochemical staining was used to investigate the distribution of c-kit positive CIC in jejunum of rats.Meanwhile,the ultrastructure of CIC was observed by electron microscope.Results: Compared with control group,the intestinal motility and the c-kit positive CIC in jejunum were both markedly decreased in model group(both P
