Clinical and pathological changes of neuromuscular complications in 7 Sjogren's syndrome cases
- VernacularTitle:干燥综合征患者伴神经系统损害7例临床及病理变化
- Author:
Yuexing LI
;
Lijuan WU
;
Qingtang CHEN
- Publication Type:Journal Article
- Keywords:
Sjogren's syndrome;
Peripheral nervous sysem diseases;
Neuromuscular diseases
- From:
Chinese Journal of Neurology
1999;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical features and pathological changes of muscles and peripheral nerves in Sjogren's syndrome cases accompanied with neuromuscular complications. Methods The muscle and peripheral nerve biopsies of 7 cases were performed and the specimens were tested by using histochemical and electron microscopic methods. Results The results revealed that myelinated fiber number in peripheral nerves was severely decreased in 2 cases, and the manifestations of atrophy, necrosis, vasculitis and mononuclear cell inflitration could be found in the muscle tissues in 5 cases. Conclusions The neurologic complications of Sjogren's syndrome appear commonly and early. The muscle and peripheral nerve biopsies indicate that complications and its degree,in patients with Sjogren's syndrome should be early diagnosed and treated.
