Changes of fibrinolytic activity and D-Dimer level in the primary hypertention of the elderly and their significance
- VernacularTitle:老年原发性高血压患者纤溶活性和D-二聚体的变化及其意义
- Author:
Jingyi ZHANG
;
Huimin YANG
;
Linjie FU
- Publication Type:Journal Article
- Keywords:
Elderly hypertension;
Plasminogen activators;
Plasminogen activator inhibitor
- From:
Clinical Medicine of China
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of plasma fibrinolytic activity and D dimer level in the primary hypertension of the elderly.Methods ELISA was applied to measure blood and urine D dimer.Chromophore substrate method was used to detect PL,Plg,t PA and PAI 1.Results The levels of PAI 1,D dimer and Plg were obviously higher in the elderly primary hypertension and hypertentive kidney disease than those in the control group,while t PA and PL activity were lower than in the control group.Conclusion The changes of PLA and D dimer play an important role in hypertension and hypertentive renal disease of the elderly,on which the early diagnosis can be based.
