Expression of nerve growth factor in sensory and motor Schwann cells
- VernacularTitle:感觉性和运动性神经来源许旺细胞神经生长因子的表达
- Author:
Yu QIN
;
Liqiang GU
;
Lanxiao WU
- Publication Type:Journal Article
- Keywords:
Schwann cell;
Nerve growth factor;
Nerve regeneration
- From:
Chinese Journal of Microsurgery
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of nerve growth factor (NGF) in sensory and motor Schwann cells and its significance in the nerve specific regeneration Method Sensory and motor Schwann cells were prepared in vitro,and each group of cells were cultured in common media and IL 1 media respectively The expression of NGF was measured by Sangwich ELISA Result Generally speaking,the expression level of sensory Schwann cells is higher than that of motor cells And the expression modes of the two types of cells are different,according to the timing and peak numbers Conclusion The NGF expressions of sensory and motor Schwann cells are different,such a difference may partly explain the mechanism of the nerve specific regeneration
