The shortand long term study of mifepristone on hysteromyoma
- VernacularTitle:米非司酮治疗子宫肌瘤的近期及远期疗效研究
- Author:
Yanxia WU
;
Shujuan YU
;
Fengzhu LI
- Publication Type:Journal Article
- Keywords:
Hysteromyoma;
Mifepristone
- From:
Clinical Medicine of China
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the short and long term effect of mifepristone on hysteromyoma.Methods The treatment group ( n=60 ) was given mifepristone and the control group ( n=60 ) vitamin C.The volume of hysteromyoma was measured using B-mode ultrasound prior to and at the end of treatment.L H,FSH,E2 progesterone ( P) ,liver function and blood creatinine were monitored each month.At the second year,3 0 cases from treatmentgroup were given mifepristone again for 3 months in the same way as the first course and with the same indexes monitored. Results Mifepristone had1 0 0 % effective rate with one-course curative rate of6.67% ,the hysteromyoma volume decreased by an average of at least 3 5.1 0 % ,while the volume gradually increased over 6months after discontinuing mifepristone with the recurrence rate of3 0 .0 0 % .At the second course of treatment hysteromyoma was further reduced by50 .2 0 % ,with the scope of reduction larger than thatatthe firstcourse( P
