A clinical study of Yangxueqingnaokeli in preventive treament of migraine
- VernacularTitle:养血清脑颗粒预防和治疗偏头痛的临床研究
- Author:
Sheng LUO
;
Xinde WANG
;
Peigen KUANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Migraine;
Drug therapy
- From:
Chinese Journal of Neurology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic efficacy and adverse-events of Yangxueqingnaokel i (main composition includes Chinese angelica, ligusticum wallichii, Paconia lac tiflora, Asarum sieboldii, etc) in patients with migraine. Methods One hundred and twelve patients with migraine with an average age of 38.1?9.8 years( ranging from 19～75) were investigated in a multicenter, doub le-blind, randomized, controlled and perspective study. Results (1) The total number an d total duration of migraine attacks were markedly decreased in therapeutic group of Yangxueqingnaokeli than those in placebo group, 3.1?2.5 and 4.2?2.7 ( Z=2.1 6, P=0.03); 31.0?48.0 and 51.2?73.8(Z=2.86, P=0.004), respe ctively. (2) The to tal decrease rate of migraine attacks (%) of therapeutic group and placebo group were 4.9?0.3 and 3.0?0.5(Z=5.76,P
