Expression of tumor necrosis factor-related apoptosis-induce ligand receptors in bladder transitional cell cancer
- VernacularTitle:TRAIL受体在膀胱癌中的表达及意义
- Author:
Zhichao ZHANG
;
Zhiqing ZHANG
;
Qiang ZHANG
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Carcinoma;
Tumor necro sis factor-related apoptosis-induce ligand (TRAIL) recptors
- From:
Chinese Journal of Urology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of tumor necrosis factor-related apoptosis-induce ligand (TRAIL) receptors in bla dder transitional cell cancer. Methods TRAIL receptors m RNA were tested by means of RT-PCR and Northern Blot in bladder transitional ce ll cancer tissue. Results The expression of death recept or 4 (DR4) and death receptor 5 (DR5) have been certificated in bladder transiti onal cell cancer and normal bladder tissue,decoy receptor 1 (DcR1) expressed onl y in normal bladder tissue. Conclusions TRAIL gene may p lay an important role in the apoptosis of bladder transitional cell cancer.
