Protective effect of liposome carried prostaglandin E_1 on skin flap ischemia reperfusion injury in rats
- VernacularTitle:脂质体携前列腺素E_1对皮瓣缺血-再灌注损伤的保护作用
- Author:
Jie GUO
;
Yongcheng XU
;
Hongchi JIANG
- Publication Type:Journal Article
- Keywords:
Liposome;
Prostaglandin E;
Flaps
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanism of protective effect of liposome carried prostaglandin E 1 (PGE 1) on rat skin flap ischemia / reperfusin(I/R). Methods Island flaps of abdomen of adult SD rats were established for ischmia reperfusion injury models. Weighting, immunocytochemistry and in situ hybridization were employed. Results It was found that treatment with liposome carried PGE 1 significantly alleviated I/R induced muscular edema, attenuated neutrophil accumulation in the I/R tissue ( P
