Cytogenetic analysis of meningiomas.
10.3346/jkms.1992.7.2.162
- Author:
Jeong Hee CHO
1
;
Gyeong Yeob GONG
;
Eun Sil YU
;
Chung Jin WHANG
;
Kwan Ja JEE
;
In Chul LEE
Author Information
1. Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Meningioma;
chromosomal analysis;
neurofibromatosis-2
- MeSH:
Adolescent;
Adult;
*Chromosome Aberrations;
Female;
Humans;
Male;
Meningeal Neoplasms/*genetics;
Meningioma/*genetics;
Neurofibromatosis 2/genetics
- From:Journal of Korean Medical Science
1992;7(2):162-166
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cytogenetic analysis of 4 cases of meningiomas from 3 male and 1 female patients is reported. One of male patients suffered from neurofibromatosis type 2. Histologically, the meningiomas were meningotheliomatous (1), transitional (2), and psammomatous (1). Chromosomal abnormalities were found in all cases with a karyotype 45,XY,-22, 45,XY,-16, 45,XX,-2, and 45,XY,t (15p;22q), respectively. Monosomy of chromosome 22 was detected only in the patient with neurofibromatosis type 2. These cytogenetic analysis demonstrates that variable clonal karyotype aberrations exist in meningiomas.