The observation of effect of lovastatin on hyperlipidemia of children with nephrotic syndrome
- VernacularTitle:洛伐他汀治疗小儿肾病综合征高脂血症的观察
- Author:
Ziming HAN
;
Xinde CHEN
;
He ZHANG
- Publication Type:Journal Article
- Keywords:
Nephrotic syndrome;
Children;
Lovasatin;
Low lipide therapy
- From:
Clinical Medicine of China
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of lovastatin on hyperlipemia of children with nephrotic syndrom.Methods 43 cases of nephrotic syndrome were randomly divided into treatment group (n=21) and control group (n=22), all of which were given prednisone.Lovastatin was added to the treatment group.Before treatment and one month after treatment liver function and serum lipide were measured.Results The levels of serum apolipoprotein B (ApoB),total cholesterol (TC), trigtycerides (TG), low density lipoprotein cholesterol (LDL C) and lipoprotein (a) (Lpa) were obviously decreased compared with that before treament (P
