Pancreatoblastoma: histopathological and ultrastructural analysis of two cases.
10.3346/jkms.1992.7.2.184
- Author:
Doo Hyun CHUNG
1
;
Chul Woo KIM
;
Tae Jung KWON
;
Je G CHI
Author Information
1. Department of Pathology Seoul National University College of Medicine, Korea.
- Publication Type:Case Reports
- Keywords:
Pancreatoblastoma;
Exocrine differentiation;
Pancreas;
Childhood
- MeSH:
Carcinoma/*pathology/ultrastructure;
Child, Preschool;
Female;
Humans;
Pancreatic Neoplasms/*pathology/ultrastructure
- From:Journal of Korean Medical Science
1992;7(2):184-188
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pancreatoblastoma has been described in children and characterized by unique histologic features and excellent clinical course. Ultrastructural and immunohistochemical studies of pancreatoblastoma reveal either exocrine alone or both endocrine and exocrine differentiation. We present two cases of pancreatoblastoma in children in which immunohistochemical and ultrastructural examination failed to demonstrate features of either enzyme or hormone production and which became worse in clinical course. We assume that pancreatoblastomas are tumors which differentiate more toward acinar or ductal elements than toward islet cell.
