The heritability of Graves′ disease and its clinical significance
- VernacularTitle:Graves病遗传度及其临床意义
- Author:
Decai CHEN
;
Weiguo JIA
;
Xia CHEN
- Publication Type:Journal Article
- Keywords:
Graves′ disease;
Heredity;
Heritability
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the heritability of Graves′ disease (GD) and to discuss its clinical significance. Methods The heritability of GD was calculated using Falconer′s formula and by investigating the GD numbers of 1968 first relatives of 526 established GD patients. Results The heritability of GD was 45%, appearantlymuchlowerthanthoseofprevious reports in China. Conclusion The onset of GD is affected by both inheritant and environmental factors, the latter seems to be predominant over the former.
