Prevalence of dementia and major subtypes in urban and rural communities of Beijing
- VernacularTitle:北京市城乡痴呆及其主要亚型的患病率
- Author:
Zhenxin ZHANG
;
Jing WEI
;
Xia HONG
- Publication Type:Journal Article
- Keywords:
Dementia;
Prevalence;
Alzheimer′s disease;
Vascular dementia
- From:
Chinese Journal of Neurology
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate epidemiological pattern of dementia and major subtypes,we conducted a prevalence survey in Beijing,China. Methods A door to door three phase procedure was used to ascertain dementia A Chinese version of Mini Mental State Examination (CMMSE) was administered to all participates in 1997 Then,those who failed the screening tests and those of the normal,but having a suspected history of cognitive impairment were interviewed by neurologists or psychiatrists for a diagnostic assessment of dementia,Alzheimer′s dementia (AD) and vascular dementia (VaD) using the DSM IV,NINCDS ADRDA,and NINCDS AIREN criteria Validity of the diagnostic approach was confirmed by a follow up study in 1998 Participants a total of 5 913 residents aged 55 years and over from 12 urban and 17 rural communities was drawn through a stratified multiple stage cluster sampling 5 743 (96 1%) were interviewed. Results A total of 262 cases of mild to severe dementia were identified The crude and age standardized prevalence in individuals aged 55 years and over were 4 6% and 4 2% for dementia (all causes),2 2% and 2 0% for AD,and 1 6% and 1 5% for VaD,respectively The prevalence of AD increased doubling every 5 years with age,but the prevalence of VaD increased low and slow The age standardized prevalence of AD was 1 7% in men lower than 2 1% in women,but the prevalence of VaD was 1 7% in men higher than 1 3% in women for individuals aged 55 years and over The difference in age standardized prevalence of AD between urban and rural communities was not significant that was 1 8% versus 2 2% in individuals aged 55 years and over; but the corresponding figures of VaD in rural (2 2%) was significantly higher than that in urban (1 0%) Either for AD or for VaD,there were no significant relationships between age standardized prevalence rates and educational levels Conclusion Our overall prevalence of dementia and its subtypes is considerably higher than previously reported estimates from China and similar to those reported in whites The epidemiological and clinical patterns for AD differed from VaD,but it was similar to those reported in whites It suggests that there are no substantial differences across cultures for AD
