Therapeutic effect of rhG-CSF on grade Ⅳ leukopenia induced by chemotherapy of malignant tumor
- VernacularTitle:重组人粒细胞集落刺激因子治疗10例恶性肿瘤化疗所致的Ⅳ度白细胞减少症
- Author:
Yuanqiang LIU
;
Jie CUI
- Publication Type:Journal Article
- Keywords:
rhG-CSF;
malignant tumor;
leukopenia
- From:
China Oncology
1998;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To study the effect of recombinated human granulocyte colony-stimulating factor (rhG-CSF,filgrastim) on leukopenia induced by chemotherapy.Methods:Ten cases of leukopenia of grade Ⅳ induced by chemotherapy of malignant tumor were treated with rhG-CSF . When WBC2.5?109/L, rhG-CSF was stopped.Results:All patients with leukopenia of grade Ⅳ recovered to normal after treatment with rhG-CSF , the average time of usage was 6.8 days. The infection rate was 60%(6/10). Conclusions:Filgrastim is effective in the treatment of leukopenia of grade Ⅳ after chemotherapy, rhG-CSF decreases infection and facilitates chemotherapy.
