Inhibitory effects of tetramethylpyrazine (TMP) on melanocytic proliferation, melanin synthesis and tyrosinase activity in vitro
- VernacularTitle:川芎嗪对体外培养的黑素细胞的抑制作用
- Author:
Shuzhong GUO
;
Linxi ZHANG
;
Zhen WANG
- Publication Type:Journal Article
- Keywords:
Tetramethyl pyrazine(TMP);
Melanocytes;
Tyrosinase;
Melanin
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the mechanism and effect of TMP on melanocytes.Methods MTT method, NaOH-assay and Takahashi method were employed to measure the proliferation, melanin synthesis, tyrosinase activity of melanocytes. Results TMP induced a mild effect on melanocytic proliferation ( p
