The correlation analysis of insulin resistance and tumor necrosis factor-? in patients with congestive heart failure in the elderly
- VernacularTitle:老年充血性心力衰竭患者胰岛素抵抗与肿瘤坏死因子-?的相关分析
- Author:
Xinqing DU
;
Chaoxiang XU
;
Yourong XU
- Publication Type:Journal Article
- Keywords:
Heart failure, congestive;
Insulin antibodies;
Hyperinsulinism;
Tumor necrosis factor
- From:
Chinese Journal of Geriatrics
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between insulin resistance (IR) and plasma tumor necrosis factor ?(TNF ?) in patients with congestive heart failure (CHF) in the elderly. Methods The levels of fasting plasma insulin (FINS) and TNF ? were determined by means of radioimmunoassay in 52 elderly patients with CHF and 36 elder healthy controls. Insulin sensitivity of CHF patients was assessed using reciprocal of the product of fasting plasma insulin and glucose (IAI). The correlation between the grades of cardiac function, left ventricular ejection fraction(LVEF) and IAI of the CHF patients and TNF ? were analyzed. Results Compared to the elder healthy controls, elder patients with CHF showed significantly higher levels of TNF ?〔(0 36?0 13) ?g/L vs (0 21?0 12) ?g/L, P
