The effects of CDK4 on proliferation of the cells in the epithelium with oral lichen planus
- VernacularTitle:CDK4对口腔扁平苔藓细胞增殖的调控作用
- Author:
Zhou WEI
;
Jin YAN
;
Wu ZHIFEN
- Publication Type:Journal Article
- Keywords:
Cyclins dependent kinases;
Mouth;
Lichen planus;
Cell division
- From:
Journal of Practical Stomatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the cause and mechanism of oral lichen planus (OLP). Methods: The expression of cyclins dependent kinases (CDK4) in epithelial cells in the samples in 40 cases of OLP and in 10 cases of healthy controls was observed by immunohistochemical method. Results: The expression indexes of CDK4 in the epithelial basal layer and spinous layer in OLP were 0. 5637 ? 0. 0201 and 0. 5388? 0. 0120, those in the healthy control were 0. 4020? 0. 0155 and 0. 3480? 0. 0163, respectively(p