Effectiveness of propafenone for paroxysmal supraventricular tachycardia
- VernacularTitle:普罗帕酮终止阵发性室上性心动过速疗效观察
- Author:
Jun KE
;
Yuanzhong LI
;
Fangzhou CHENG
- Publication Type:Journal Article
- Keywords:
Propafenone;
Tachycardia;
Therapeutic effect
- From:
Clinical Medicine of China
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy and safety of propafenone on paroxysmal supraventricular tachycardia (PSVT).Methods 37 patients with PSVT were injected with 70 mg propafenone intravenously in 5 minutes.The unrecovered patients in 20 minutes were injected with 70 mg propafenone intravenously again,who were given 70 mg propafenone intravenously once again if not controlled in late 30 minuted.Blood pressure,heart beat,12 lead electrocardiogram were recorded before and after use of drug.Results The significant effective rate was 77.5% and effective rate was 21.6% with overall effective rate of 97.3% and effective time of 1～55 (7.1?2.8) minutes.The average accumulated dose of propafenone was 105 mg.Some side effects were observed in part of patients,including slight reduction of blood pressure,P R interval.QRS wave and Q T interval prolonged,temporary type sino atrial block,vertigo and nausea,etc whice could vanish gradually if not treated.Conclusion Propafenone by intravenous injection can quickly contro PSVT with saftey and effectiveness.
