The protective effect of losartan on diabetic nephropathy
- VernacularTitle:洛沙坦在糖尿病肾病中的保护作用
- Author:
Juping CHANG
;
Xueqing YU
;
Jun ZHANG
- Publication Type:Journal Article
- Keywords:
Losartan;
Diabetic nephropathy;
Enalapril
- From:Clinical Medicine of China
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effects of angiotensin Ⅱ receptor antagonist losartan on diabetic nephropathy (DN).Methods 37 DN cases complicated by renal insufficiency were divided into two groups which were treated with losartan and enalapril,respectively.Blood pressure,plasma creatinine,blood urea nitrogen (BUN),uricemia,urinary protein and albumin were measured before and at 2,4,8,12 weeks after treatment.Results Losartan and enalapril lowered blood pressure remarkably (P0.05).Losartan decreased uricemia remarkably (P
