Histopathological changes of skin in freckle patients after phenol chemical peel
- VernacularTitle:苯酚化学剥脱术后雀斑皮肤组织的病理变化
- Author:
Qiming ZHAO
;
Zhiyong CHEN
;
Chengju ZHANG
- Publication Type:Journal Article
- Keywords:
Freckle;
Phenol;
Chemical peeling
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the histopathological changes of skin after phenol chemical peeling.Methods Immunohistochemical staining (ABC method) and transmission electron microscopy were used to investigate the skin of changes 15 cases of freckle.Results After phenol chemical peeling,the melansomes in basal layer cells decreased dramatically, the elastic and collagenous fibers in dermis enlarged ,and the skin thickened .Conclusions After phenol chemical peeling,the melansomes in cuticular layer cells decrease remarkably and the freckle disappears.The proliferative activitities of fibroblasts in dermis have been improved,resulting in thickness of elastic and collagenous fibers in dermis. It may be the reason why the skin delays to be aged.
