Interference effect of Anisodamine on plasma endotoxin cousing renel damage in patients with obstractive jaundice
- VernacularTitle:654-2对梗阻性黄疸内毒素致肾脏损害的临床干预
- Author:
Mingrong HU
- Publication Type:Journal Article
- Keywords:
Cholestasis;
Endotoxin;
Greatinine;
Anisodamine
- From:
Chinese Journal of Current Advances in General Surgery
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the plasma endotoxin(ET)on renal damage and clinical interference of anisodamine in patients with obstractive jaundice(OJ).Methods: Thirty patients with OJ were randomly divided into general treatment group(A group) and anisodamine treatment (B jroup).The level of plasma ET and endogenous creatinine clearance rate(Ccr) were determined at perioperative period,other 21 cases of chronic choelithiasis without jaundice were employed to serve as the control.Results: (1)The plasma ET level of peripheral blood was increased significantly and Ccr level was decreased markedly in both A and B group than in the control at lst day of hospitalization(P