Clinical comparison of the sensitivity and specificity of cardiac troponin I and cardiac troponin T and creatine kinase MB for the early diagnosis of acute myocardial infarction
- VernacularTitle:心肌肌钙蛋白I、肌钙蛋白T、肌酸激酶同工酶MB早期诊断急性心肌梗死敏感性及特异性比较分析
- Author:
Ying ZUO
;
Ruizhen JIA
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Cardiac troponin I;
Cardiac troponin T;
Creative kinase MB;
DiagnosiT
- From:Clinical Medicine of China
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the application value of cardiac troponin I (cTnI),cardiac troponin T (cTnT) and creatine kinase MB (CK MB) for the early diagnosis of acute myocardial infarction (AMI).Methods The same serum sample was measured to detect the indexes of cTnI,cTnT and CK MB levels in 60 patients with AMI and 40 patients with UA.Comparison between AMI and UA was performed and all the indexes were analysed contrastively.Results The sensitivity of cTnI and cTnT was higher than that of CK MB,and their positive rates were 63.3%,46.7% and 18.3% respectively (P0.05) and the specificity of the three indexes were almost the same without significant difference.Conclusion cTnI and cTnT,as specific markers of cardiac damage,are more sensitive and specific in the early diagnosis of AMI.As a convenient,swift and accurate measurement method,cTnI has significant clinical value.
