A study on the adaptive mechanism of peripheral nerve to gradual limb lengthening: observation on the perineurial barrier and vascular permeability
- VernacularTitle:周围神经适应缓慢牵伸的机制研究——兔胫后神经血-神经屏障及束膜屏障观察
- Author:
Jianzhong XU
;
Qihong LI
- Publication Type:Journal Article
- Keywords:
Tibia;
Bone lengthening;
Tibial nerve;
Rabbi
- From:
Chinese Journal of Orthopaedics
1996;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of limb lengthening on the perineurial barrier and vascular permeability of peripheral nerve. Methods Thirty-two rabbits with limb lengthening of 10％ , 20％ , 30％ and 40％ were used in this study; 8 animals were allocated in each group. Sixteen were employed for the electron microscopic(EM) observation and the others for the investigation of perineurial barrier and vascular permeability of the tibial nerves. Results Even if the elongation reached 40％ of the original length of the tibia, both the perineurium and inner membrane of capillary was still intact, the perineurial barrier and vascular permeability maintained normal; however, EM examination revealed increase of a large number of vacuoles and the increase of the number of mitochondria in the cell of the perineurial membrane. Conclusion It is the gradual limb lengthing of
