THE EXPRESSION OF LYSOZYME IN CARCINOMA OF AMPULLA CORRELATED WITH INVASION,METASTASIS AND PROGNOSIS
- VernacularTitle:溶菌酶在壶腹癌分型中的临床意义
- Author:
Xiuguo ZHANG
;
Nanhai SHUO
;
Xihong JIANG
;
Kesen XU
;
Xushong JIANG
- Publication Type:Journal Article
- Keywords:
Carcinoma of the ampulla;
Lysozyme;
Neoplasm metastasis
- From:
Chinese Journal of Current Advances in General Surgery
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of lysozyme in ampullary carcinoma, and its relation with invasion, metastasis and prognosis. Methods: 36 cases were analyzed with immunohistochemistry of lysozyme. Results: The lysozyme-positive rate in patients with lymph node metastasis (30%) was significantly lower than that in patients without metastasis (71%), while that in patients with advanced cancer invading the pancreas (35%), was significantly lower than that in patients with cancer without invasion of the pancreas. The Survival rate of lysozyme-positive patients (66.7%) was significantly higher than that of lysozyme-negative patients (14.3%). Conclusion: The expression of lysozyme in carcinoma of ampulla is associated with invasion, metastasis and prognosis. Lysozyme is important in typing of cancer of ampulla.
