MECHANISM OF INSULIN RESISTANCE IN PATIENTS WITH IMPAIRED GLUCOSE TOLERANCE AND TYPE II DIABETES MELLITUS
- VernacularTitle:用改进的最小模型对糖耐量减退和Ⅱ型糖尿病患者胰岛素抵抗致病机制的研究
- Author:
Hong XIA
;
Jiawei CHEN
;
Jie SHEN
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type II Insulin resistance Glucose tolerance, im-paired
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Insulin sensitivity index (SI).glucose effectiveness (SG) and insulin secretion function were assessed by modified minimal model method (MMM) with frequently sampled intravenous glucose tolerance (FSIGT) test in the controls, in patients with impaired glucose tolerance (IGT), and type II diabetes mellitus (NIDDM). There was significant correlation between modified MMM and standard MMM in evaluating SI and SG. The results indicated that SI and SG were significantly elevated in the control than in the IGT and NTDDM groups. SI diminished much more in IGT group than in NIDDM group (P
