DISTRIBUTION AND SIGNIFICANCE OF FACTOR X-LIKE ANTIGEN IN PANCREATIC ISLETS AND THEIR TUMOURS
- VernacularTitle:胰岛及其肿瘤中第X因子样抗原的分布及其意义
- Author:
Jiyao YU
- Publication Type:Journal Article
- Keywords:
Factor X Islet Endocrine tumour, pancreatic Immunohistochemistry
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The factor X-like antigen in normal pancreatic islets and in 52 cases of pancreatic endocrine tumours was investigated by immunohistochemistry. It was found that A cells and PP cells showed positive immunostaining for factor X-like antigen. Benign glucagonomas and PP-omas presented the highest concentrations of the immunoreactive material. Some benign insulinomas also presented factor X-like antigen. In malignent endocrine tumours of the pancreas immunohistochemical expression of factor X-like antigen was generally low or absent. The possible implications of the present findings for coagulative disorders associated with endocrine tumours were discussed.
