CHANGES IN IL-2/IL-2R SYSTEM IN GRAVES DISEASE
- VernacularTitle:Graves病患者IL-2/IL-2R系统的改变
- Author:
Jianmin LIU
;
Wanling WU
;
Bingfa ZHU
- Publication Type:Journal Article
- Keywords:
Graves disease Interleukin-2 Interleukin-2R-? cell sIL-2R
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Changes in IL-2/IL-2R system in 25 patients with thyrotoxic Graves disease and 20 eu-thyroids were investigated and compared with those of 15 normal controls. The thyrotoxic patients showed a high concentration of serum sIL-2R and a large amount of circulating IL-2R-?- cells but a decreased production of IL-2 by PBMC. However, these abnormalities had a tendency to become normal with improvement of the disease. The IL-2 was correlated with the percentage of IL-2R-?- cells and sIL-2R. This study may provide clues to the im-munopathogenesis in Graves Disease.
