The regulation of Guzhen Fang on the neuroendocrine and immunol systems of rats injected by cyclophoshamidum
- VernacularTitle:固真方对环磷酰胺大鼠神经内分泌及免疫系统部分功能的调节作用
- Author:
Changquan LING
- Publication Type:Journal Article
- Keywords:
Guzhen Fang;
Cyclophshamidum;
Neuroendocrine Immunity;
Wistar rats
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The changes of monoamine neurotransmitters in hypothalamus,luteinizine hormone(LH),estrediol(E_2),testosterone(Ts)in serum,?-endorphin(?-EP)in plasma and the immunity oflymphocytes in spleen of rats injected by cyclophoshamidum(Cy)were observed.In the sametime we shudied the effects of Guzhen Fang(GZF)on the pathological changes caused by Cy.the results were as following:1.After the rats were injected by Cy,the contents of monoamineneurotransmitters in hypothalamus disordered,?-EP in plasma increaed greatly,the function ofhypothalamus-hypophsis-gonadal(HHG)axis and immunity of lymphocytes in spleen decreasedevidencely.2.GZF could correct above-mentioned disorders.3.Si Junzi Tang could also increasethe function of immunity as well as GZF.but the range of regulation of it on the neuroendocrinesystem is narrower than that of GZF.
