THE OBSERVATION OF ULTRASTRUCTURAL CHANGE IN ATRIAL MYOCARDIUM BIOPSY FROM VENTRICULAR SEPTAL DEFECT WITH PULMONARY HYPERTENSION
- VernacularTitle:室间隔缺损并肺动脉高压心肌超微结构改变的观察
- Author:
Zhaozhi LI
;
Xigang GENG
;
Luanxian LIANG
- Publication Type:Journal Article
- Keywords:
ventricular septal defect(VSD);
pulmonary hypertension (PH);
atrial myocardium biopsy;
ultrastructure
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The electromicroscopic observation of atrialbiopsy was carried out in 10 patients with ventric-ular septal defect (VSD) and middle, severe pul-monary hypertension (PH). The observation sug-gests that there are myofibrillar lysis to disappearwith various degrees, dilated rough endoplasmreticulum and the increase in lipofuscin granulesand lipid droplets; mitochondral hyperplasia, theirsize and shape being different, disorganizing of mi-tochondria, disintegration of cristae, mitochondralretrograde degenration and decreased matrix elec-tron density. The dilated intercalated discs and in-crease in myocardial fibrous tissue were found inpart of patients. These structural changes areprobably due to chronic myocardial ischemia.
