Precursor B-Cell Acute Lymphoblastic Leukemia in Two Patients with a History of Cytotoxic Therapy.
- Author:
Suk Pyo SHIN
1
;
Sang Hee SONG
;
Eun Jung KO
;
Ji Su KIM
;
Chi Young PARK
;
Doyeun OH
;
So Young CHONG
Author Information
1. Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea. sychong@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Precursor B-cell acute lymphoblastic leukemia;
Cytotoxic therapy;
Therapy-related leukemia
- MeSH:
Humans;
Korea;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Precursor Cells, B-Lymphoid
- From:Korean Journal of Medicine
2013;85(1):96-100
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Therapy-related myeloid neoplasms have been well characterized. However, precursor B-cell acute lymphoblastic leukemia in patients with prior malignancies is uncommon, and the effect of prior cytotoxic therapy on development of precursor B-cell acute lymphoblastic leukemia is controversial. Therapy-related precursor B-cell acute lymphoblastic leukemia has been reported occasionally. However, cytotoxic therapy-related precursor B-cell acute lymphoblastic leukemia has been reported in Korea only rarely. We herein describe two cases of therapy-related precursor B-cell acute lymphoblastic leukemia.
