AN ENDOCRINE STUDY OF REPRODUCTIVE SUCCESS AND FAILURE AFTER CLOMIPHENE-INDUCED OVULATION
- VernacularTitle:氯菧酚胺疗效及失败的内分泌因素
- Author:
Jinfang LIN
- Publication Type:Journal Article
- Keywords:
Clomiphene Luteinized unruptured follicle Reproductive hormonal assay : Cervical score
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Thirty-three anovulatory, infertile patients under clomiphene (CC) treatment were studied. Out of the 33 patients with 83 treatment cycles, 32 cases with 64 cycles presented ovulatory responses. Only 12 patients (37.5%) conceived.Through ovarian function monitoring by BBT, cervical score (GS), reproductive hormonal assays and serial ultra-sonography, it was found that of 64 cycles which presented ovulatory responses, only 37 cycles (51.8%) showed actual ovu-lation; follicles in 27 cycles (42.2%) were unruptured but luteinized (LUF). The incidence of reoccurrence of LUF in repeated CG treatment cycles was 83.3%. There was no evidence that CG adversely affected the CS after 5-day treatment. And luteal function was normal in the above ovulatory cycles. We consider LUF to be an important cause in the failure to achieve pregnancy.Through investigation of some related parameters, including reproductive hormone assay, the key points of successful induction of ovulation and mechanisms causing LUF were analysed.
