EFFECTS OF Zn~(2+) ON THE NEUROMUSCULAR TRANSMISSION
- VernacularTitle:Zn~(2+)对神经肌接头传递的作用
- Author:
Yinfu QI
;
Xiping CHE
- Publication Type:Journal Article
- Keywords:
neuro-muscular junction;
phrenic nerve diaphragm;
Zn~(2+);
L-cystein
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Experiments were carried out on the isolatedrat phrenic nerve diaphragm preparations and chickbiventer cervicis preparations. Zn~(2+) at cumulativeconcentration inhibited muscle contractile responseto indirect stimulation without affecting the con-ductivity of nerve. The inhibiting. action of Zn~(2+) onthe muscle contractile response to indirect stimula-tion was stronger than that on contractile responseto direct stimulation. Zn~(2+) did not affect the Achsensitivity of the chick biventer cervicis muscleThe effects of Zn~(2+) on neuromuscular transmis-sion were antagonized by Ca~(2+) and L-cystein.
