Effect of Naloxone on Central Conductive Function in Expermental Acute Spinal Cord Injury
- VernacularTitle:纳洛酮对实验性脊髓损伤的中枢传导功能的作用
- Author:
Liansheng LIU
- Publication Type:Journal Article
- Keywords:
Spinal cord injury Naloxone MEP CSEP
- From:
Chinese Journal of Trauma
1990;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The experimental acute spinal cord injury (SCI) was performed in 10 rabbits at L_1 level using the method of compredssing the abdominal lateral of spinal cord. The rabbits were treated with naloxone (2mg/kg/h) intravenously 45 minutes after SCI and treated continually for 4 hours. In the control group, equal volume of saline was administered. The ascending and descending conductive function of spinal cord was measured by mortor evoked potential (MEP) and cortical somatosensory evoked potential (CSEP). The result showed that amplitude of the MEP and CSEP peaks came to a normal level 2 hours after SCI and were significantly higher (P
