Hemorrhagic Fever with Renal Syndrome (HFRS) Virus Infected Hrman Umbilical Vein Endothelial (HUVE) Cells Decrease in Susceptibility to NK and LAK Cytotoxicity
- VernacularTitle:肾综合征出血热病毒感染的人脐带静脉内皮细胞降低对NK、LAK杀伤作用的敏感性
- Author:
Yin LIU
;
Bequan JIN
;
Zhikai XU
;
Xuesong LIU
- Publication Type:Journal Article
- Keywords:
Hemorrhagic fever with renal syndrome virus;
Endothelial cells;
NK;
LAK
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The cultured HUVE cells were infected with HFRS veruses. At different intervals after in-fection cytotoxicity of NK and LAK by 4 hours Cr release method. It was found that the infec-tion of endothelial cells inhibit the lytic activity of NK and LAK cells. Theinhibition. It is sug-gested that the deceased susceptibility of HFRS virus infected endothelial cells to NK and LAKcells may protect the viruses from the cellular immunity during the course of HFRS.
