EFFECTS OF Zn~(2+) ON ISOLATED SUPERIOR CERVICAL SYMPATHETIC GANGLION OF RABBITS
- VernacularTitle:Zn~(2+)对兔离体颈上交感神经节的作用
- Author:
Yinfu QI
;
Xiping CHE
- Publication Type:Journal Article
- Keywords:
Zn~(2+);
sympathetic ganglion;
action potentials;
neostigmine;
1-cystein;
sucrose-gap method
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of Zn~(2+) on the isolated superior cervical sympathetic ganglion of rabbit were stud ied with sucrese-gap method. It was found thatZn~(2+) significantly inhibited ganglienic action poten-tial with a manner of concentration-dependence.The IC-50 value was 1. 48 mmol/L. The effects ofZn~(2+) were antagonized by neostigmine and 1-cys-tein, reduced under high concentration of Ca~(2+) andenhanced under low concentration of Ca~(2+). It wasalso found that Zn~(2+) inhibited ganglionic N wave,less affected p wave and without any effect on LNwave.
