AN IMMUNOHISTOCHEMICAL STUDY OF ADENOID CYSTIC CARCINOMA OF THE SALIVARY GLANDS
- VernacularTitle:涎腺腺样囊性癌的免疫组化研究
- Author:
Shuzhen WANG
;
Yongsheng HU
;
Xumin ZHAO
- Publication Type:Journal Article
- Keywords:
adenoid cystic carcinoma;
immunohistochemistry;
S-100 protein;
vimentin;
Keratin.
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Three antibodies were used for immunohistochemical study of 15 cases of adenoid cystic carcinoma(6 cases contained normal salivary gland tissue). The results indicated that myoepithelial cell of the normal salivary glands revealed positive reaction of S-100 protein; The basal cells of the straited ducts and excretary ducts revcaled strong positive reaction of keratin. In adenoid cystic carcinoma positive reaction of S-100 prctein and vimentin were found in luminal cells of cribriform pseudocyts and peripheral cells of tumor nests, and the outer layers'cells of tubular stucture and the border cells of trabucula. But the positive reaction of keratin was found in inner cells of tubular and central cells of trabecular patten. It indicated that adenoid cystic carcinoma probably stems from the basic cells of the striated ducts and excretary ducts of normal salivary glands.
