Sequence Anal ysis of HLA—DRw 12 Subtypes Found in Chinese Homozygous Cells
- VernacularTitle:从DRB基因核苷酸顺序分析中国人DR_w12纯合细胞的D_w多态性
- Author:
Peihua LU
- Publication Type:Journal Article
- Keywords:
HTC;
DRw12 Subtype;
Nucleotide Sequence Analysis;
HLA—DRB Gene
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
We determined the nucleotide sequences of enzymatically amplified second exons of DRB1and DRB3 genes derived from three Chinese DRw12 homozygous cells and found two distinctDRw12 haplotypes.The combinations between DRB1 and DRB3 genes of the two haplotypeswere different from that in Caucasoid DRw12 HTCa.Thise result might explain the consquenceof generating“new”Dw specificities by cellular assay.
