EFFECT OF Se ON Na~+ ,K~+-ATPase AND 5'-NUCLEOTIDASE ACTIVITIES OF CARDIAC SARCOLEMMA IN RATS
- VernacularTitle:硒对大鼠心肌细胞膜Na~+,K~+—ATP酶及5'—核苷酸酶活性的影响
- Author:
Lanhua ZHOU
;
Chao LI
;
Guanglu XU
- Publication Type:Journal Article
- Keywords:
selenium;
Na~+ ,K~+ —ATPase;
15'—nucleotidase;
rat;
cardiac sarcolemma
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Sprague—dawey rats were fed for one to three months with Se—deficient grains from Keshan disease area, Se—supplemented diet and stock diet,respectively. Changes of Na~+ ,K~+ ATPase and 5'—nucleotidase activities in cardiac sarcolemma ,Se Contents in liver and plasma and GSH—px activities in Liver and red blood cells of rats were observed. The results showed that Na~+ ,K~+—ATPase. and 5'—nucleotidase activities in cardiac sarcolemma in Se-deficient group rats were significantly decreased,hepatic and plasma Se contents as well as hepatic and erythrocyte GSH—px activities were also significantly decreased at of feeding 30,60 and 90 d as compared to Se—supplemented or stock diet group. There was no significant difference in these parameters between Se—supplemented or stock diet groups There was no significant difference in these paramefers between Se—supplemented and stock diet groups。
