SEQUENTIAL DETERMINATIONS OF SERUM SPECIFIC IgG ANTIBODIES OF PATIENTS WITH EPIDEMIC HEMORRHAGIC FEVER AND THEIR RELATIONSHIP TO ILLNESS TYPES
- VernacularTitle:EHF患者特异性IgG动态变化及其与病型的关系
- Author:
Zhengwen LIU
;
Chengwen ZHANG
;
Xiuru LI
- Publication Type:Journal Article
- Keywords:
hemorrhagic fever,epidemic;
antibody, viral;
IgG;
illness type
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Serum specific IgG (SIgG) antibodies of 32 patients with epidemic hemorrhagic fever (EHF) were sequentially determined by indirect immunofluorecent antibody test and their relationship to the types of the disease were analyzed in the present paper. The SIgG antibodies appeared practically on day 3 after the onset of the disease. Thereafter,the positive rates and the SIgG titres increased with the prolongation of the illness days and reached 100% positive rates and stable high titres till day 11 to day 12 after the onset of the disease. Furthermore, different types of the disease had.different SIgG response curves ,and there was a significant difference between the SIgG titres of different illness types statistically from day 7 to day 8 after the onset of the disease. These results suggest that the SIgG might be responsible for the immunopathogenesis of EHF.
